Research on CBD Oil for Sleep/Insomnia

In a pre-clinical study, researchers found that CBD boosted wakefulness and inhibited slow-wave and REM sleep. It increased alpha brain waves, which promoted alertness, and suppressed delta waves, which are surprisingly needed for deep sleep. Please note that this was only a pre-clinical study.
Another study revealed that CBD wanes-off the roots of insomnia. Being an anti-anxiolytic, CBD fights off anxiety, a common factor that is responsible for causing insomnia. 
Studies of blood tests have proven that CBD oil influences the dopamine levels in our bloodstream during sleep. This leads to a better and more relaxed sleep.

How CBD affects Sleep ?
Cannabidiol works with the body’s endocannabinoid system (ECS), which is responsible for all the homeostatic functions of the body. Today it is understood that CBD tends to regulate balance and homeostasis in the human body making it simpler for you to fall asleep. It is also believed that CBD affects sleep cycles.

As of now, researchers understand that sleep is divided into multiple cycles with different phases. CBD oil increases the third phase, which is the phase of deep sleep. Furthermore, CBD decreases the duration of the REM sleep, which is a phase of light sleep. This is also the phase where dreams occur. By reducing the REM sleep, people dream less, memory is improved, and symptoms of depression are decreased.

Effects of acute systemic administration of cannabidiol on sleep-wake cycle in rats.


Cannabidiol (CBD) is one of the main components of Cannabis sativa and has a wide spectrum of action, including effects in the sleep-wake cycle.


The objective of this paper is to assess the effects on sleep of acute systemic administration of CBD.


Adult male Wistar rats were randomly distributed into four groups that received intraperitoneal injections of CBD 2.5 mg/kg, CBD 10 mg/kg, CBD 40 mg/kg or vehicle (n=seven animals/group). Sleep recordings were made during light and dark periods for four days: two days of baseline recording, one day of drug administration (test), and one day after drug (post-test).


During the light period of the test day, the total percentage of sleep significantly increased in the groups treated with 10 and 40 mg/kg of CBD compared to placebo. REM sleep latency increased in the group injected with CBD 40 mg/kg and was significantly decreased with the dose of 10 mg/kg on the post-test day. There was an increase in the time of SWS in the group treated with CBD 40 mg/kg, although this result did not reach statistical significance.


The systemic acute administration of CBD appears to increase total sleep time, in addition to increasing sleep latency in the light period of the day of administration.

The results of these findings show great promise for CBD. When taken at the correct strength and dose it shows capability for treating insomnia and generally improving sleep.

To discuss any of these findings please contact us

The content on these pages are in no way intended to offer any related health benefits to our products but merely to share opinions and any research findings.

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